Welcome to Rat BodyMap database
Rat BodyMap database is a freely and user-friendly accessible database providing enormous rat RNA-Seq gene expression profiles. By using the Illumina HiSeq 2000 platform, the data were generated from 320 individual RNA samples derived from 32 Fischer 344 rats, containing ten organs per rat (i.e., adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testis or uterus), and at four developmental stages (8 rats, 4 male and 4 female, per stage) (i.e., early immature, 2 weeks old; puberty, 6 weeks old; adult, 21 weeks old; and aged, 104 weeks old).
For each sample, we aligned the trimmed reads to the genome and annotated to AceView genes consisting of 65,167 specific transcripts corresponding to 40,064 genes. A significant number of genes and transcripts were differentially expressed among different organs and developmental stages. Every individual differentially expressed gene could be easily explored on the database. In addition, to enlarge the scope of the database, the data have been linked to widely-used genetic and functional databases.
Because the rat is extensively used for evaluating drug and chemical toxicities and for understanding drug mechanisms, Rat BodyMap is expected to be highly useful for biomedical research.